| Name |
Valacyclovir hydrolase |
| Synonyms |
9137 |
| Gene name |
BPHL |
| General function |
Involved in hydrolase activity |
| Specific function |
Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes |
| Gene sequence |
+ ...
ATGCCCAGGAATCTGCTTTATTCTCTTTTGTCCTCCCACCTGTCCCCCCATTTCAGCACCTCGGTAACCTCTGCCAAAGTGGCTGTGAATGGCGTTCAGCTGCATTACCAGCAGACTGGAGAGGGAGATCACGCAGTCCTGCTACTTCCTGGGATGTTAGGAAGTGGAGAGACTGATTTTGGACCTCAGCTCAAGAACCTCAATAAGAAGCTCTTCACGGTGGTCGCCTGGGATCCTCGAGGCTATGGACATTCCAGGCCCCCAGATCGCGATTTCCCAGCAGACTTTTTTGAAAGGGATGCAAAAGATGCTGTTGATTTGATGAAGGCGCTGAAGTTTAAGAAGGTTTCTCTGCTGGGGTGGAGTGATGGGGGCATAACCGCACTCATTGCTGCTGCAAAATATCCATCTTACATCCACAAGATGGTGATCTGGGGCGCCAACGCCTACGTCACTGACGAAGACAGCATGATATATGAGGGCATCCGAGATGTTTCCAAATGGAGTGAGAGAACAAGAAAGCCTCTAGAAGCCCTCTATGGGTATGACTACTTTGCCAGAACCTGTGAAAAGTGGGTGGATGGCATAAGACAGTTTAAACATCTCCCAGATGGTAACATCTGCCGGCACCTGCTGCCCCGGGTCCAGTGCCCCGCCTTGATTGTGCACGGTGAGAAGGATCCTCTGGTCCCACGGTTTCATGCCGACTTCATTCATAAGCACGTGAAAGGCTCACGGCTGCATTTGATGCCAGAAGGCAAACACAACCTGCATTTGCGTTTTGCAGATGAATTCAACAAGTTAGCAGAAGACTTCCTACAATGA
|
| Protein sequence |
+ ...
MVAVLGGRGVLRLRLLLSALKPGIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ
|
| GO Classification |
| function |
| catalytic activity |
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www.drugbank.ca
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