DT-Web

DNA-directed RNA polymerase subunit alpha


Partner ID 6769
Name DNA-directed RNA polymerase subunit alpha
Synonyms 7622
Gene name rpoA
General function Transcription
Specific function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Gene sequence + ...

ATGAAGGTGCGCGCGTCGGTCAAGAGGATCTGCGACAAGTGCAAGGTGATCCGCCGGCACGGGCGGGTCTACGTCATCTGCGAGAACCCCAAGCATAAGCAGCGGCAGGGTTAG
Protein sequence + ...

MLDSKLKAPVFTVRTQGREYGEFVLEPLERGFGVTLGNPLRRILLSSIPGTAVTSVYIEDVLHEFSTIPGVKEDVVEIILNLKELVVRFLNPSLQTVTLLLKAEGPKEVKARDFLPVADVEIMNPDLHIATLEEGGRLNMEVRVDRGVGYVPAEKHGIKDRINAIPVDAVFSPVRRVAFQVEDTRLGQRTDLDKLTLRIWTDGSVTPLEALNQAVEILREHLTYFSNPQAAAVAAPEEAKEPEAPPEQEEELDLPLEELGLSTRVLHSLKEEGIESVRALLALNLKDLKNIPGIGERSLEEIKEALEKKGFTLKE
GO Classification
component
cell
intracellular
function
transferase activity, transferring phosphorus-containing groups
nucleic acid binding
DNA binding
binding
nucleotidyltransferase activity
DNA-directed RNA polymerase activity
catalytic activity
protein dimerization activity
protein binding
transferase activity
process
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
physiological process
transcription
metabolism
cellular metabolism
transcription, DNA-dependent
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB08266 methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate

Associated as Prediction

Id Name
DB04788 Tagetitoxin
DB08226 Myxopyronin B
DB08266 methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate
↑