DT-Web

Dihydrofolate reductase-like protein 1


Partner ID 6504
Name Dihydrofolate reductase-like protein 1
Synonyms 8701
Gene name DHFRL1
General function Coenzyme transport and metabolism
Specific function Not Available
Gene sequence + ...

ATGTTTCTTTTGCTAAACTGCATCGTCGCTGTGTCCCAAAACATGGGCATCGGCAAGAACGGGGACCTGCCCAGGCCGCCGCTCAGGAATGAATTCAGGTATTTCCAGAGAATGACCACAACTTCTTCAGTAGAGGGTAAACAGAATCTGGTGATTATGGGTAGGAAGACCTGGTTCTCCATTCCTGAGAAGAATCGACCTTTAAAGGATAGAATTAATTTAGTTCTCAGCAGAGAACTCAAGGAACCTCCACAAGGAGCTCATTTTCTTGCCAGAAGTTTGGATGATGCCTTAAAACTTACTGAACGACCAGAATTAGCAAATAAAGTAGACATGATTTGGATAGTTGGTGGCAGTTCTGTTTATAAGGAAGCCATGAATCACCTAGGCCATCTTAAACTATTTGTGACAAGGATCATGCAGGACTTTGAAAGTGACACGTTTTTTTCAGAAATTGACTTGGAGAAATATAAACTTCTGCCTGAATACCCAGGTGTTCTCTCTGATGTCCAGGAGGGGAAACACATCAAGTACAAATTTGAAGTATGTGAGAAGGATGATTAA
Protein sequence + ...

MFLLLNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINLVLSRELKEPPQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSSVYKEAMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPEYPGVLSDVQEGKHIKYKFEVCEKDD
GO Classification
function
coenzyme binding
NADP binding
binding
catalytic activity
oxidoreductase activity, acting on the CH-NH group of donors
oxidoreductase activity
oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
dihydrofolate reductase activity
cofactor binding
process
serine family amino acid metabolism
glycine metabolism
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
physiological process
nucleotide metabolism
metabolism
nucleotide biosynthesis
cellular metabolism
amino acid metabolism
glycine biosynthesis
amino acid and derivative metabolism
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB01929 5-Chloryl-2,4,6-Quinazolinetriamine
DB01958 5-[4-Tert-Butylphenylsulfanyl]-2,4-Quinazolinediamine
DB02001 5-(4-Morpholin-4-Yl-Phenylsulfanyl)-2,4-Quinazolinediamine
DB02402 5-(4-Methoxyphenoxy)-2,4-Quinazolinediamine
DB04163 5-Phenylsulfanyl-2,4-Quinazolinediamine
DB04306 5-[(4-Methylphenyl)Sulfanyl]-2,4-Quinazolinediamine
DB07862 7-(1-ETHYL-PROPYL)-7H-PYRROLO-[3,2-F]QUINAZOLINE-1,3-DIAMINE
DB08203 7-[2-METHOXY-1-(METHOXYMETHYL)ETHYL]-7H-PYRROLO[3,2-F] QUINAZOLINE-1,3-DIAMINE

Associated as Prediction

Id Name
DB01929 5-Chloryl-2,4,6-Quinazolinetriamine
DB01958 5-[4-Tert-Butylphenylsulfanyl]-2,4-Quinazolinediamine
DB02001 5-(4-Morpholin-4-Yl-Phenylsulfanyl)-2,4-Quinazolinediamine
DB02402 5-(4-Methoxyphenoxy)-2,4-Quinazolinediamine
DB03814 2-(N-Morpholino)-Ethanesulfonic Acid
DB04163 5-Phenylsulfanyl-2,4-Quinazolinediamine
DB04306 5-[(4-Methylphenyl)Sulfanyl]-2,4-Quinazolinediamine
DB07862 7-(1-ETHYL-PROPYL)-7H-PYRROLO-[3,2-F]QUINAZOLINE-1,3-DIAMINE
DB08203 7-[2-METHOXY-1-(METHOXYMETHYL)ETHYL]-7H-PYRROLO[3,2-F] QUINAZOLINE-1,3-DIAMINE
↑