DT-Web

Ribonuclease 4


Partner ID 3511
Name Ribonuclease 4
Synonyms 5549
Gene name RNASE4
General function Involved in nucleic acid binding
Specific function This RNase has marked specificity towards the 3' side of uridine nucleotides
Gene sequence + ...

ATGGCTCTGCAGAGGACCCATTCATTGCTTCTGCTTTTGCTGCTGACCCTGCTGGGGCTGGGGCTGGTCCAGCCCTCCTATGGCCAGGATGGCATGTACCAGCGATTCCTGCGGCAACACGTGCACCCTGAGGAGACAGGTGGCAGTGATCGCTACTGCAACTTGATGATGCAAAGACGGAAGATGACTTTGTATCACTGCAAGCGCTTCAACACCTTCATCCATGAAGATATCTGGAACATTCGTAGTATCTGCAGCACCACCAATATCCAATGCAAGAACGGCAAGATGAACTGCCATGAGGGTGTAGTGAAGGTCACAGATTGCAGGGACACAGGAAGTTCCAGGGCACCCAACTGCAGATATCGGGCCATAGCGAGCACTAGACGTGTTGTCATTGCCTGTGAGGGTAACCCACAGGTGCCTGTGCACTTTGACGGTTAG
Protein sequence + ...

MALQRTHSLLLLLLLTLLGLGLVQPSYGQDGMYQRFLRQHVHPEETGGSDRYCNLMMQRRKMTLYHCKRFNTFIHEDIWNIRSICSTTNIQCKNGKMNCHEGVVKVTDCRDTGSSRAPNCRYRAIASTRRVVIACEGNPQVPVHFDG
GO Classification
function
endoribonuclease activity, producing 3'-phosphomonoesters
pancreatic ribonuclease activity
binding
catalytic activity
hydrolase activity
nucleic acid binding
hydrolase activity, acting on ester bonds
nuclease activity
endonuclease activity
endoribonuclease activity
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB03448 2'-Deoxyuridine 3'-Monophosphate

Associated as Prediction

Id Name
DB00128 L-Aspartic Acid
DB00536 Guanidine
DB01812 Adenosine-3'-5'-Diphosphate
DB01842 3'-Phosphate-Adenosine-5'-Diphosphate
DB01942 Formic Acid
DB01961 Cytidine-3'-Monophosphate
DB02098 Adenosine-2'-5'-Diphosphate
DB02363 2'-Monophosphoadenosine-5'-Diphosphate
DB02573 2'-Deoxycytidine-2'-Deoxyadenosine-3',5'-Monophosphate
DB02714 3'-Uridinemonophosphate
DB02805 1-(3-O-Phosphono-Beta-L-Arabinofuranosyl)Pyrimidine-2,4(1h,3h)-Dione
DB02987 Cysteine-S-Acetamide
DB03155 1-(2-Deoxy-2-Fluoro-3-O-Phosphono-Beta-L-Ribofuranosyl)Pyrimidine-2,4(1h,3h)-Dione
DB03186 U-Pi-a-Pi
DB03326 deoxycytidylyl-3',5'-guanosine
DB03431 Adenosine-5'-Diphosphate
DB03447 Uridylyl-2'-5'-Phospho-Adenosine
DB03448 2'-Deoxyuridine 3'-Monophosphate
DB03512 Uridine-2',3'-Vanadate
DB03726 Purine Riboside-5'-Monophosphate
DB03765 Cytidine-2'-Monophosphate
DB03792 5-Amino-1h-Pyrimidine-2,4-Dione
DB03900 2-Methyl-2-Propanol
DB04272 Citric Acid
DB04464 N-Formylmethionine
DB04514 Phosphoric Acid-2'-[2'-Deoxy-Uridine]Ester-5'-Guanosine Ester
DB08596 5'-deoxy-5'-piperidin-1-ylthymidine
DB08661 1-(2,5-dideoxy-5-pyrrolidin-1-yl-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
↑