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Acetolactate synthase, catabolic


Partner ID 2786
Name Acetolactate synthase, catabolic
Synonyms 4763
Gene name budB
General function Amino acid transport and metabolism
Specific function 2 pyruvate = 2-acetolactate + CO(2)
Gene sequence + ...

ATGGACAAACAGTATCCGGTACGCCAGTGGGCGCACGGCGCCGATCTCGTCGTCAGTCAGCTGGAAGCTCAGGGAGTACGCCAGGTGTTCGGCATCCCCGGCGCCAAAATCGACAAGGTCTTTGATTCACTGCTGGATTCCTCCATTCGCATTATTCCGGTACGCCACGAAGCCAACGCCGCATTTATGGCCGCCGCCGTCGGACGCATTACCGGCAAAGCGGGCGTGGCGCTGGTCACCTCCGGTCCGGGCTGTTCCAACCTGATCACCGGCATGGCCACCGCGAACAGCGAAGGCGACCCGGTGGTGGCCCTGGGCGGCGCGGTAAAACGCGCCGATAAAGCGAAGCAGGTCCACCAGAGTATGGATACGGTGGCGATGTTCAGCCCGGTCACCAAATACGCCATCGAGGTGACGGCGCCGGATGCGCTGGCGGAAGTGGTCTCCAACGCCTTCCGCGCCGCCGAGCAGGGCCGGCCGGGCAGCGCGTTCGTTAGCCTGCCGCAGGATGTGGTCGATGGCCCGGTCAGCGGCAAAGTGCTGCCGGCCAGCGGGGCCCCGCAGATGGGCGCCGCGCCGGATGATGCCATCGACCAGGTGGCGAAGCTTATCGCCCAGGCGAAGAACCCGATCTTCCTGCTCGGCCTGATGGCCAGCCAGCCGGAAAACAGCAAGGCGCTGCGCCGTTTGCTGGAGACCAGCCATATTCCAGTCACCAGCACCTATCAGGCCGCCGGAGCGGTGAATCAGGATAACTTCTCTCGCTTCGCCGGCCGGGTTGGGCTGTTTAACAACCAGGCCGGGGACCGTCTGCTGCAGCTCGCCGACCTGGTGATCTGCATCGGCTACAGCCCGGTGGAATACGAACCGGCGATGTGGAACAGCGGCAACGCGACGCTGGTGCACATCGACGTGCTGCCCGCCTATGAAGAGCGCAACTACACCCCGGATGTCGAGCTGGTGGGCGATATCGCCGGCACTCTCAACAAGCTGGCGCAAAATATCGATCATCGGCTGGTGCTCTCCCCGCAGGCGGCGGAGATCCTCCGCGACCGCCAGCACCAGCGCGAGCTGCTGGACCGCCGCGGCGCGCAGCTCAACCAGTTTGCCCTGCATCCCCTGCGCATCGTTCGCGCCATGCAGGATATCGTCAACAGCGACGTCACGTTGACCGTGGACATGGGCAGCTTCCATATCTGGATTGCCCGCTACCTGTACACGTTCCGCGCCCGTCAGGTGATGATCTCCAACGGCCAGCAGACCATGGGCGTCGCCCTGCCCTGGGCTATCGGCGCCTGGCTGGTCAATCCTGAGCGCAAAGTGGTCTCCGTCTCCGGCGACGGCGGCTTCCTGCAGTCGAGCATGGAGCTGGAGACCGCCGTCCGCCTGAAAGCCAACGTGCTGCATCTTATCTGGGTCGATAACGGCTACAACATGGTCGCTATCCAGGAAGAGAAAAAATATCAGCGCCTGTCCGGCGTCGAGTTTGGGCCGATGGATTTTAAAGCCTATGCCGAATCCTTCGGCGCGAAAGGGTTTGCCGTGGAAAGCGCCGAGGCGCTGGAGCCGACCCTGCGCGCGGCGATGGACGTCGACGGCCCGGCGGTAGTGGCCATCCCGGTGGATTATCGCGATAACCCGCTGCTGATGGGCCAGCTGCATCTGAGTCAGATTCTGTAA
Protein sequence + ...

MDKQYPVRQWAHGADLVVSQLEAQGVRQVFGIPGAKIDKVFDSLLDSSIRIIPVRHEANAAFMAAAVGRITGKAGVALVTSGPGCSNLITGMATANSEGDPVVALGGAVKRADKAKQVHQSMDTVAMFSPVTKYAIEVTAPDALAEVVSNAFRAAEQGRPGSAFVSLPQDVVDGPVSGKVLPASGAPQMGAAPDDAIDQVAKLIAQAKNPIFLLGLMASQPENSKALRRLLETSHIPVTSTYQAAGAVNQDNFSRFAGRVGLFNNQAGDRLLQLADLVICIGYSPVEYEPAMWNSGNATLVHIDVLPAYEERNYTPDVELVGDIAGTLNKLAQNIDHRLVLSPQAAEILRDRQHQRELLDRRGAQLNQFALHPLRIVRAMQDIVNSDVTLTVDMGSFHIWIARYLYTFRARQVMISNGQQTMGVALPWAIGAWLVNPERKVVSVSGDGGFLQSSMELETAVRLKANVLHLIWVDNGYNMVAIQEEKKYQRLSGVEFGPMDFKAYAESFGAKGFAVESAEALEPTLRAAMDVDGPAVVAIPVDYRDNPLLMGQLHLSQIL
GO Classification
function
binding
vitamin binding
thiamin pyrophosphate binding
catalytic activity
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB01987 Thiamin Diphosphate
DB02327 2-[2-(2-Hydroxy-Ethoxy)-Ethoxy]-Ethanol
DB03361 2-{(9as)-9a-[(1s)-1-Hydroxyethyl]-2,7-Dimethyl-9a,10-Dihydro-5h-Pyrimido[4,5-D][1,3]Thiazolo[3,2-a]Pyrimidin-8-Yl}Ethyl Trihydrogen Diphosphate

Associated as Prediction

Id Name
DB00507 Nitazoxanide
DB01987 Thiamin Diphosphate
DB02280 (R)-Mandelic Acid
DB02327 2-[2-(2-Hydroxy-Ethoxy)-Ethoxy]-Ethanol
DB02410 2-Acetyl-3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-4-Methyl-5-(4,6,6-Trihydroxy-3,5-Dioxa-4,6-Diphosphahex-1-Yl)Thiazolium Inner Salt P,P'-Dioxide
DB02743 Beta-1,4-Galactobioside
DB03147 Flavin-Adenine Dinucleotide
DB03361 2-{(9as)-9a-[(1s)-1-Hydroxyethyl]-2,7-Dimethyl-9a,10-Dihydro-5h-Pyrimido[4,5-D][1,3]Thiazolo[3,2-a]Pyrimidin-8-Yl}Ethyl Trihydrogen Diphosphate
DB04248 Beta-1,4-Galactotrioside
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